I have this model and it took a while to work out how to get the scanner to locate the application list. I created the links from within any of the applications that I might use it with (eg photo editors, word recognition programmes, etc.) and now I seem to have all the appropriate options come up in the front screen. If you still have problems go to the Lexmark tech support website and give them as much info as possible and you should get a response fairly quickly.
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I have the same problem with my Lexmark 5400 series. Computer is the Dell Inspiron with Vista Premium.
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