Best Windows Registry Tweak Program to protect your online security

Sounds like spyware.have you tried using a spyware remover?Go to downloads.com search for malwarebytes,download it ,install to your computer.Run it do a full system scan,it will remove spyware and hopefully that popup.
Good luck

Its a virus.
You need to run these 3 essential programs to remove all the spyware on your computer.

If you do not have an internet security suit and only an anti virus
1. Run Malwarebytes Anti-Malware
2. Run a complete scan with free curing utility Dr.Web CureIt!
3. Run the anti spyware removal programs spybot or Superantispyware
Use Mozilla firefox or the google chrome browser for browsing unsafe websites

Install ThreatFire.ThreatFire, features innovative real-time behavioral protection technology that provides powerful standalone protection or the perfect complement to traditional signature-based antivirus programs offers unsurpassed protection against both known and unknown zero-day viruses, worms, trojans, rootkits, buffer overflows, spyware, adware and other malware.
Run an online virus scan like Trend Micro HouseCall,F-Secure Online Virus Scanner etc etc
update your software by running
Secunia Online Software Inspector
Install a good antivirus in your computer.
Keep your antivirus updated. If automatic updates are available, configure your antivirus to use them.
Keep your permanent antivirus protection enabled at all times.

1. Download Spybot Search and Destroy.
2. Boot your computer in safe mode (tap F8 during the restart process).
3. Scan/Remove any spyware that Spybot detects.

If this is still an issue, a simple Google search for "spyware remover" will yield millions of results. Just make sure that you run the spyware remover in safe mode to ensure that it catches spyware that is already running on your system.