My softail doesn't pick up when opening the gas handle. Cleaning the carb didn't help

Remove the air filter cover and the air filter so that you can see into your carb. Start the engine and allow it to warm up a bit. Keep your face a safe distance from the carb and rev the engine moderately. Watch to see if the slide moves up and down. If it does not move, you may have a hole in the vacuum diaphragm that controls the slide and it's not allowing your slide to be raised. If the slide is moving, your main jet is probably clogged. You'll have to remove the float bowl and the jet and clean it out. Check the slow speed jet as well. It's in a hole just to one side of the main jet holder. Also notice whether or not you see a squirt of fuel come out of the brass nozzle just inside of the mouth of the carb. If you do not see the fuel squirt into the carb when you open the throttle, you accellerator pump diaphragm may need to be replaced. It's located under a plate on the bottom of the float bowl.

Good Luck
Steve