Have a spark plug not firing.

Are you sure it's actually a plug?
Are you getting oil on the plug?
The plug may be firing but you may be losing compression which gives the symptoms of a misfire. As you've changed the plug, lead and coil this points to to a problem elsewhere.

Your first course of action should be to get a mobile mechanic carry out a diagnostic check for you.

To put your mind at rest, do a 2nd compression test using a light oil squirted into the bores:

Doing a Compression Test
Warm the engine. Remove all the spark plugs.
Get a pencil and piece of paper to note down the readings.
Put the compression tester into the No1 cylinder and crank the engine for 10 seconds.
Note down the compression reading.
Repeat process for all cylinders.

Here's an illustration of what you may expect on a 4 cylinder engine:
Cylinder 1 2 3 4
psi 125 122 120 124

125 is the uppermost figure for that engine. Here, this engine is fine. There's a slight variation in psi figures, but that's perfectly normal.

Here's the same engine:
Cylinder 1 2 3 4
psi 110 112 114 112

The psi reading is down. However, as all the figures are pretty much equal it doesn't indicate head /gasket problems. It may point towards worn pistons or burnt valves.

Now consider these psi readings:
Cylinder 1 2 3 4
psi 125 84 86 124

There's more than a 10% drop - a difference - between cylinder 1 and 2, and cylinders 3 and 4.
The compression readings for cylinders 2 and 3 is down; low. There's something clearly wrong.

It suggests that there is a defective head gasket between cylinders 2 and 3 or a crack in the cylinder head. The rising piston compresses the gases which escape into the adjoining cylinder via the defective gasket or cracked head.

However, it could also mean that there is a problem with the valves (burnt/not seating properly) or perhaps piston / ring problems.

A burnt valve - it's usually the exhaust valve as they bear the brunt of the combustion - can cause a reduction in engine power simply because the combustion process isn't occurring properly. Compressed air/fuel gets squeezed out of that cylinder because of the damaged valve . There even may be a misfire - a surge as the car runs.

Worn or broken piston rings allow compressed gases to leak past into the crankcase. A compressed crankcase can force oil out of the dipstick tube. The pressure in the crankcase will leak to atmosphere anywhere it can find an outlet.

The 2nd Compression Test
The second compression test is known as a 'wet test'. The first compression test was the dry test because no oil was added to the bores. The second 'wet' test can give an indication of whether it is the rings or valves at fault (though bear in mind rings and valves do not cause overheating or water in the coolant symptoms).

Spray a liberal amount of light penetrating oil into each cylinder - aim for the cylinder walls, not the centre of the piston. You want the oil to run down the cylinder wall and around the piston to form a seal.

Place a rag over each spark plug hole and spin the engine to eject the surplus oil.

Then carry out a full compression test noting down the results.

Here's the previous results with the 2nd compression readings added:
Cylinder 1 2 3 4
psi 125 84 86 124
Wet 128 112 110 126

The readings have increased. This because the oil sprayed into the bores has formed a temporary seal around the piston, thereby enabling the compression to be raised. It also indicates that the bores/rings are worn on cylinder 2 and 3 - the 'oil seal' has increased the readings but is still low in comparison with cylinders 1 and 2.

This could also indicate that in addition to worn rings there is also burnt valves. Oil cannot form a seal around a valve. A worn or split valve will cause a low compression reading and misfiring symptoms.
Compressions readings should be taken in conjunction with other symptoms. It will help you identify the problem:

Low compression readings between two adjoining cylinders point towards a head gasket/head fault if your vehicle has shown signs of coolant loss, coolant in the oil system - mayonnaise, overheating, rough running and lack of power.

If those symptoms are not present it points towards burnt valves/piston rings. A worn engine may be difficult to start and pressurise the crankcase, but it doesn't cause overheating problems.

Make sure the plugis firing to eliminate the coil and sparkplug. All you need to do since your compression levels are not great but are ok. Pull the plug out put it in the end of coil/or e end of wire, then place the screwed end on something metal for a ground then start the vehicle quickly and check the plug to see if it is igniting. Or if you do not want to deal with the compressiin from engine disable the fuel pump relay, itwill run for awhile then not start up at all. While disabled have someone crank the engine over while you make sure the plug is grounded. The reasons for a dead cylinder could be a plugged fuel injector too.