Car started not running smoth. seems like a plug mis fire. could it be plug or coil pack

Replace the coil pack.

The coils have battery voltage running through the primary windings, and grounded in the ignition control module. The engine computer signals the ignition module when to cut the primary current, thereby inducing high voltage in the coil's secondary windings and spark at the spark plug.
The computer processes all sensor information, but primarily from the crank position sensor, to determine spark timing.

Try to see if you can get view the are where the plugs are firing in the dark. Check for arcing off the plug or wires to the metal engine parts. I fought with a vehicle for days trying to determine a misfire problem on a car that we just put new plugs, wires, and coils on. Turns out the ceramic insulator on one of the BRAND NEW plugs had a hairline crack down the length of the insulator. You could not see if with the naked eye, but you could feel it if you ran your finger over it. Easiest to find if you can run the engine in a dark garage.

could be valve probs or piston. do a pressure test that will tell if it is or not. hope this helps

There can be other reasons for misfires beside spark plugs/coil, such as a bad injector, low compression in that cylinder, burnt valve seats.

Replaced the MAF sensor - nothing. Took it to a authorized toyota shop & checked compression which check out good and put the computer on. Computer read mis-fire on cylinder 1, and then multiple misfire (like it would jump around). We went ahead and replaced the fuel injector on cylnder 1 - did not solve problem as when we hook the computer up, misfire seemed tp stay at idle and seem better when running high RMP, but check engine light is on as it never went away. Went ahead and replaced the coil pack to cylinder 1 - nothing. what am i missing?

bad ignition control module its under the coil packs

Do you have coil over each plug or is it a coil pack for all plugs. If each plugs has a coil, they have small screws to remove, pull the plug wire out after this. But if the coil pack, label each plug wire to keep them in order. the pack can be removed easily. It should have 4 screw, once those are out the coil pack will come off. Make sure after replacing it, you use di-electric grease on the bottom of the pack or in the coil over plug method. This keeps run-away spark and can cause mis-fire.

you could have a bad tork converter clutch and you could have a bad injector. also the new wire or plug could be defective but is not likely. Did you gap the new plug?

IS THIS A 99 CROWN VIC? IF SO IS IT MISFIRING? IF THIS IS THE CASE YOU MORE THAN LICKLY NEED PLUG WIRES.

Btw, I’m available to help over the phone in case u need at https://www.6ya.com/expert/terry_db4da071b7da3ac1