Sounds like the lock actuator is either not getting power,or it lost it's ground. If all the other locks work ok, remove panel on tailgate and put a "stab-light' on the red or hot wire at the actuator. If the light goes on when you hit the key fob,and the lock does nothing, you need a new actuator.
{: ) You didn't mention what vehicle you have, but anyway, for 2003 models, it is most likely a faulty liftgate actuator.
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