The power door locks are controlled by the BCM -body control module ! The door lock switch is an input to the BCM .
The BCM, upon receipt of a door lock switch lock or unlock signal, will switch the appropriate door lock actuator control circuits to battery positive voltage. The opposing side of the door lock actuators are connected to ground internally within the BCM through the other door lock actuator control circuit and the doors will lock or unlock appropriately.
First thing to do would be check power an ground circuits at the BCM ! Do you have any other systems not working -power windows etc...
The DR/LCK fuse supplies battery positive voltage to the I/P fuse block for the door lock system. The body control module (BCM) supplies and monitors a reference voltage to the door lock switch through the door lock switch lock/unlock signal circuit. The door lock switch also receives a constant ground source. If a door lock switch is placed in the lock position or unlock position, the reference voltage is taken directly to ground and the BCM detects the voltage drop on the signal circuit.
Should have BCM checked for stored DTC'S - diagnostic trouble codes !
Ignition ON, observe the scan tool Driver Door Lock Sw, Psgr Door Lock Sw, Driver Door Unlock Sw and Psgr Door Unlock Sw parameters while using the driver and passenger door lock switches. The parameters should change between Active and Inactive.
If the values does not change between the commanded states, refer to Door Lock Switch Malfunction.
Command the driver door and passenger door lock actuators to LOCK and UNLOCK with the scan tool, the doors should LOCK and UNLOCK when changing between commanded states.
If a door lock actuator does not perform the LOCK and UNLOCK functions, refer to Door Lock Malfunction
DTC B3130 00: All Door Unlock Circuit
DTC B3135 00: All Door Lock Circuit