2000 4 runner v6 4x4 is starting to miss fire, i put new plugs in did not help

Only other two option are the coils and the injectors'

With engine running unplg one coil at a time feling for the one that does NOT stumble the engine. The one that doesnt is the dead cylinder. Then rotate the coil to another cylinder. If the misfire follows it to coil then the coil is bad. If it doesnt then the injector is bad or clogged. Before replaceing it spray some water on the intake gasket to verify you do not have a leak .near that misfiring cylinder. If you do then the gasket is the problem. You should feel the engine stumble is its leaking