I have a 04 f150 that will sometimes start and run for about 2 sec. and sometime it will start right up we replaced the fuel pump and the filter and had a wire replaced from the pats system (ground) still doing it!

Man that can be several things check the fuel pump and then the fuel filter

If your engine light is on, check for codes. Sounds like fuel pump relay.

Fuel pump driver module is bad .
F150 Expedition No Start P1233 Fuel Pump Driver Module

could be the fuel filter is plugged

replaced pump and filter?

could be the cam sensor....and maybe cracked cap, bad plugs cloged fuel filter bad wires...

start with the fuel filter, located on the frame of the truck, sometimes the intial boost from the fuel pump when you start it will push through all right, but once it runs through for a min. the sentiments will setle in the filter and strve the truck, it may also be an issue with a fuel pressure regualtor, a bad injector, or a bad fuel pump, but id start with the filter, cheapest an easiest repare in the bunch

I guess there could be debris in the tank - but the fuel filter will catch it and clog up (is that a hint, or what),

Other possible is the ignition coil... the are plastic inside and they dry out and crack inside.... when they are hot - open circuit... When they are cool, closed circuit - working...

so, next time it dies, check for spark. Otherwise, replace the fuel filter (hopefully you have one OUTSIDE the fuel tank).
Let us know - please... -Jim

try replacing the throttle position sensor

when u turn the key to run but don't start the fuel pump shuts off after 5 seconds + or - 2 seconds, this is normal, the common cause of no start on your truck is the TFI ignition module on the distributor, subject of many recalls for failing, also change the stator inside the distributor, use factory parts, aftermarket parts fail very quickly. here is a picture of the parts.
This is the stator

This is the TFI ignition module.