1989 s10 instrumentpannel 5amp fuse blew and i replaced .

check to see if one of the hot wires is chaffing to the ground/or rubbing into the frame

have you checked the ECM fuse (5AMP) for the computer,sometimes they will open up and w/o the computer the fuel pump is dead also

There is an illumination fuse located in the dash fuse box. It is typically a 5amp fuse. Pull the fuse out and see if it is blown. Try replacing the fuse and see if it blows again, if it does there may be an additional problem.
Good luck.

more than one injector fuse may have blown

you have a shorted out circuit in the wiring, check harnesses for worn spots and run tests from light switch to taillights, detective work

at least you know were to start,key on the fuse that blew.and everything controlled by it.i'm assuming that every time you replace the fuse now,it blows .think back before the short,was there any electricial problems,or devices that didnt work.,wires are melted together,or motors are shorted out.putting a bigger fuse in probably burnt a wire open(meaning got too hot and broke)whatever blew the fuse to start with,is most likley where the meltdown is ,start unplugging the things on that fuse,one at a time,remove tail lightbulbs,inspect thre sockets,look up under the dash at the wiring ,your clock,tach.and gas gauge ,are there,observation is almost 90%of trouble shooting anything .fixing it is easy pop the hood spend some time just looking at every thing follow wires make sure they arent melted together ,and are plugged in,just unplugging something and plugging it back in will show problems,things will fall apart.clips will break and hopefully you will see something obvious,shorts are never fun,do you have any electrical background?and know how to use a multimeter .if you do reply ,

You most likely jumped timing and blew a head gasket.

Sounds like the the parking light fuse blew.Under the dash there is a fuse block.you will see fuses there and remove the fuse to see if blown.If so replace with same type fuse.Anymore questions will be glad to help you...

Is the climate control out also? If so it is fuse 10 (5amp) interior fuse panel.

There may be a voltage regulator in the dash that shorted out