“ESC Activation/Malfunction Indicator Light” comes on continuously with the engine running, a malfunction has been detected in the ESC system.

when you turn on your ignition to the point before engaging the starter all your warning lights should light up. The Engine Check Light is very obvious, except they throw convention to the wind and show it as 'Service Engine Soon' lamp 'Malfunction indicator lamp (MIL)'.
Page 63 - Section 2-7 Instruments and controls

Malfunction indicator lamp (MIL) If this indicator lamp comes on steady or blinks while the engine is running, it may indicate a potential emission control malfunction. The malfunction indicator lamp may also come on steady if the fuel filler cap is loose or missing, or if the vehicle runs out of fuel. Check to make sure the fuel filler cap is installed and closed tightly, and that the vehicle has at least three gallons of fuel in the fuel tank. After a few driving trips, the lamp should turn off if no other potential emission control system malfunction exists.

http://www.vadennissanservicecontracts.com/owners-manual/nissan/2001-Nissan-Frontier.pdf

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Powertrain Malfunction (Wrench) Warning Indicator (base instrument cluster)
The instrument cluster receives the powertrain status from the PCM over the high speed CAN. When a powertrain system concern is detected, the PCM sends the instrument cluster a command signal to illuminate the powertrain malfunction (wrench) warning indicator. If the 4WD control module detects a failure with the 4WD drive system, the 4WD control module sends a message to the instrument cluster over the CAN to illuminate the powertrain malfunction (wrench) warning indicator. On 4.6L engines, if the transmission control module (TCM) detects a failure with the transmission, the TCM sends a message to the instrument cluster over the CAN to illuminate the powertrain malfunction (wrench) warning indicator.
better have it checked !
Bett

Hey Earl, what's going on ? The air bag module is usually under the passenger seat or the center console ! The only way to turn off the light is with a up grade scan tool , not code reader. An the light is on for a reason , problem with the system ! If you don't know about this don't mess with it , you could deploy an air bag !
The AIR BAG indicator, located on the instrument panel cluster (IPC) is used to notify the driver of SIR system malfunctions and to verify that the SDM is communicating with the IPC. When the ignition is turned ON, the SDM is supplied with ignition 1 voltage and requests the IPC to flash the AIR BAG indicator 7 times. While flashing the indicator, the SDM conducts test on all SIR system components and circuits. If no malfunctions are detected the SDM will communicate with the IPC through the class 2 serial data circuit and request the IPC to turn the AIR BAG indicator OFF. The SDM provides continuous monitoring of the air bag circuits by conducting a sequence of checks. If a malfunction is detected the SDM will store a diagnostic trouble code (DTC) and request the IPC to turn the AIR BAG indicator ON. The presence of a SIR system malfunction could result in non-deployment of the air bags. The AIR BAG indicator will remain ON until the malfunction has been repaired.

All you have to do to reset the TPMS light is make sure all your tires are set around 35-38 psi then drive it a a couple miles and the light will turn off. If it is blinking then you have a sensor issue and you will have to take it to the dealer. The tire pressure warning light is yellow not red."Your vehicle has also been equipped with a TPMS malfunction indicator to indicate when the system is not operating properly. The TPMS malfunction indicator is combined with the low tire pressure telltale. When the system detects a malfunction, the telltale will flash for approximately one minute and then remain continuously illuminated. This sequence will continue upon subsequent vehicle start-ups as long as the malfunction exists. When the malfunction indicator is illuminated, the system may not be able to detect or signal low tire pressure as intended. TPMS malfunctions may occur for a variety of reasons, including the installation of replacement or alternate tires or wheels on the vehicle that prevent the TPMS from functioning properly. Always check the TPMS malfunction telltale after replacing one or more tires or wheels on your vehicle to ensure that the replacement or alternate tires and wheels allow"

{: ) If the malfunction indicator light is on, it means that your engine modules had detected inconsistencies , specially the emission systems. The engine control modules continuously monitor signals from various sensors and makes constant calculations based on predetermined calibrations. If the feedback gathered is in conflict with its programmed instructions, it will set a code and will request the cluster to turn on the malfunction indicator light.
You may find or feel that your engine is working fine, at the moment, but this issue shoud not be ignored. Small things can become worse if not anticipated earlier.
Tou can try this: Turn off all loads and the ignition switch. key out. Open then close driver door. Wait for 1 minute to reset. Then try to start, and check if the light will go off. If not, its advisable to have your vehicle scanned forn codes to determine the cause.

you can find that out by simply having the fault codes read

A malfunction indicator lamp (MIL), commonly referred to as the "Check Engine Light" is an indicator of malfunction of the computerized engine management system. It is found on the instrument console of most automobiles. When illuminated, it is typically either an amber or red color. On vehicles equipped with OBD-II, the light has two stages: steady (indicating a minor fault such as a loose gas cap or failing oxygen sensor) and flashing (indicating a severe fault, that will eventually destroy the catalytic converter, such as a misfire). When the MIL is lit, the engine control unit stores a fault code related to the malfunction, which can be retrieved with a scan tool and used for further diagnosis. The malfunction indicator lamp is usually labeled with the text check engine, service engine soon, check engine soon, or a picture of an engine.
The MIL appeared in the early 80s along with computerized engine controls. Even the earliest systems, such as GM's CCC (Computer Command Carburetor) system had self diagnosis functionality. When the computer detected a fault, it illuminated the MIL. Up until OBDII, on most cars the MIL could output codes, when two pins on the ALDL are jumped, the light would flash the codes, for instance (blink) (pause) (blink) (blink) for code 12. Some manufacturers retained this feature even after OBDII, such as Honda.

Hope this help (remember comment and rated this). Good luck.

usually a sensor has gone bad. have it check by a mechanic on the computer.

P0650 Malfunction Indicator Lamp (MIL) Control Circuit Malfunction

Malfunction Indicator Lamp (MIL) is located on the instrument panel. When the ignition switch is turned ON without engine running, MIL will light up. This is a bulb check. When the engine is started, MIL should go off. If MIL remains on, the on board diagnostic system has detected an engine system malfunction.

Possible Causes:

Harness or connectors (MIL circuit is open or shorted.)

MIL bulb may be faulty

The Malfunction Indicator Lamp or MIL (Also called the check engine light or service engine soon light) comes on when the on board computer detects an issue with the operation of the engine or transmission.

The best thing to do is to take the vehicle to an auto parts store like Autozone and have them hook up their scan tool to the vehicle and read the code. They can read it, tell you what it is and also tell you what the code means.

If it is pointing to a faulty component or sensor and you replace or repair the component the the light will go off on its own after the computer sees that the malfunction is no longer present.

You can have the code cleared, but if whatever caused the light to come on in the first place is not addressed then it will just come back on eventually.