Drivers door lock will lock but not unlock with switch or remote

no you needs a new lock actuator on that door its about $90 installed,
all the locks are on same circuit . sorry about the bad news :(

The locks on your vehicle are electronically controlled by the BCM - body control module . The driver an passenger door switche's are input's to the BCM . Do you know anything about automotive electronic's ? anti theft alarm remote, could this be part of the problem , No it's just a key less entry remote , nothing to do with the anti-theft .
Door Lock System Components
The Power Door Lock System consists of the following components:
• Body control module (BCM)
• Driver door lock switch
• Front passenger door lock switch
• Door lock actuators in each of the doors
• IBCM (PWR) 15-amp fuse

Door Lock System Controls
The Power Door Lock System is controlled by the body control module (BCM) and can be activated by any one of the following:
• A door lock switch Lock or Unlock actuation
• A keyless entry transmitter actuation
• An automatic door lock actuation
• An automatic door unlock actuation
• A last door closed locking (LDCL) actuation

Driver and Passenger Door Unlock Operation w/o Keyless Entry
When the body control module (BCM) detects a transition of either of the door lock switches to the Unlock position, it switches the door lock actuator unlock control circuits to voltage. Since the door lock actuator lock control circuit is at ground potential within the BCM, the driver passenger door lock actuators transition to the Unlock position.

Your best bet , take your vehicle to a qualified repair shop ! Need special tool to diagnose .

Power Door Locks Inoperative

Install a scan tool.
Turn ON the ignition, with the engine OFF.
With a scan tool, observe the door lock switch parameter in the Doors data list.
Does the scan tool display Idle?
YES - Go to Step 4
NO - Go to Step 8
4
Activate the driver door lock switch to the LOCK and UNLOCK positions.
Does the scan tool display Idle?
YES - Go to Step 9
NO - Go to Step 5
5
Activate the front passenger door lock switch to the LOCK and UNLOCK positions.
Does the scan tool display Idle?
YES - Go to Step 9
NO - Go to Step 6
6
With a scan tool, observe the driver door lock actuator command and the passenger door lock actuator command parameters in the Doors data list.
Activate a door lock switch to the LOCK and UNLOCK positions.

Try reporgraming it

1. Start with key out of ignition, drivers door is open all others closed and
drivers door is unlocked.
2. Insert key into the ignition (Do NOT Turn) and Pull key out.
3. Perform these steps within 40 seconds.
A. Using the power lock switch on the drivers door, perform 5 lock/unlock cycles
starting with lock. Use an even pace and try to go about one cycle per second.
(1Cycle = 1 lock and 1 unlock).
B. Close, then open drivers door.
4. Perform these steps within 40 seconds.
A. Using the power lock switch on the drivers door, perform 5 lock/unlock cycles
starting with lock. Use an even pace and try to go about one cycle per second.
(1Cycle = 1 lock and 1 unlock).
B. Insert the key in the ignition cylinder.
C. Turn the ignition to ON (Do NOT Start) then back to OFF.
D. Remove the key from the ignition.
5. Press any button on remote for a minimum of 1 second.
System should now lock and unlock doors once.

6. Close and open drivers door.
7. Press any button on remote for a minimum of 1 second. System should now lock and
unlock doors. Once to confirm programming, twice to indicate programming failed.
8. Repeat steps 5, 6 and 7 for additional remotes.

reprogram the remote transmitter. first leave driver door open all other doors closed,key removed from the ignition switch. insert key into the ignition switch,then remove it.press lock and unlock on the vechicle door lock control switch at 1 second intervals 5 times. close and repoen drivers door.press lock and unlock on the vechicle lock control switch at 1 second intervals 5 times. insert key into ignition switch. switch ignition on and off twice to program a remote transmitter code whilst erasing the original codes or three timre to check how many remote transmitters are currently registered.remove key from the ignition switch.system should now lock and unlock.twice to indicate programming mode or one to four times,slowly to indicate number of remote transmitters registered.for the solara press and hold lock and unlock remote buttons together, press lock remote button for a second period of 1 second. system should now lock and unlock vechicle.once to confirm, twice to indicate registration has failed.if required repeat button procedure to program remaining remote transmitters.note to exit programming mode close drivers door or insert ignition key.maximum of 4 remote transmitters can be programmed.if akk failed let dealership reprogram remote transmitters.

Remote Transmitter Replacement (Wagon)
Use the following procedure when replacing one or both remote transmitters:

1. Open the driver's door.
2. Press and hold the driver's master door lock switch down in the UNLOCK position.
3. Quickly insert and remove the key from the ignition switch five times, then insert the key the sixth time, and leave it in the ignition switch. (This routine must be done within 1O seconds.) All the doors will lock and unlock to indicate that the control unit is in the program mode.
4. Press either button on the replacement transmitter. All the doors except the driver's door will lock and unlock to indicate that the control unit has accepted the transmitter into its memory. If either transmitter button is pressed again, all the doors will lock and unlock.
5. To program a second transmitter, press either button on that transmitter. The doors should lock and unlock as described in step 4.
6. Release the driver's master door lock switch.
7. To exit the program mode, close the driver's door or remove the key from the ignition switch.

Does the switch inside for that door work ? Does the power window work for that door ? Check fuse DDM - 15 amp I/P fuse panel . Do you know where the insturment panel fuse box is located ?
Fuse Block - I/P
Left of the I/P behind the side trim panel
# 4
DDM Fuse
15A
Driver Door Module (DDM)

Do you know anything about automotive electronic's , control module's ? Serial data communication networks ?
Circuit/System Description
The driver and passenger door lock and side window switches are integrated control module switch assemblies. The DDS and PDS door lock switches are normally open, 2 position rocker type switches, with detents for lock and unlock. The DDS and PDS are directly connected to the respective door lock actuator through the door lock actuator control circuits. When a door lock or unlock function is activated from the DDS or PDS, a serial data message lock or unlock command is sent to the other door switch and body control module.

Programming
When
Remote control added or replaced. System malfunction.
How
Obtain all remote controls. Remove key from ignition switch. Close all doors. Open driver's door. Carry out the following within 24 seconds: Turn ignition switch ON and back to LOCK position 3 times. Remove key. Press and release driver's door courtesy light switch 3 times. Ensure doors lock and unlock. If not, wait 40 seconds and repeat procedure starting with driver's door already open. Press each remote control lock or unlock button twice. Ensure doors lock and unlock after each remote control operation. If not, proceed as follows: Press and release driver's door courtesy light switch once. Ensure doors lock and unlock twice. Repeat procedure starting with driver's door already open.
NOTE: A maximum of 3 remote controls can be programmed.

Programming
When
Remote control buttons operated repeatedly while vehicle out of range and system becomes inoperative. System malfunction.
How
Ensure ignition switched OFF and all doors closed. Proceed as follows: Within 10 seconds, open driver's door and switch ignition ON. Within 10 seconds of switching ignition ON, switch ignition OFF. Within 20 seconds of switching ignition OFF, press and release driver's door contact switch 3 times. Within 10 seconds of releasing driver's door contact switch, switch ignition ON then OFF. Within 20 seconds of switching ignition OFF, press and hold both remote control buttons in turn for at least 5 seconds. The driver's door should lock and unlock once. Within 5 seconds of driver's door locking/unlocking, press remote control lock button Fig. 1 [1] or unlock button [2]. Programming procedure complete. Confirm programming has been successful by locking and unlocking vehicle.
NOTE: A maximum of 2 remote controls can be programmed.

Sounds like your remote reciever unit has gone bad.

Btw, I’m available to help over the phone in case u need at https://www.6ya.com/expert/sean_54c3a3dc48a7773c

To program a remote... note that you must not delay more than 10 seconds between any of the operations.

Driver's door open, all other doors closed, key removed from the ignition switch.

Insert key into ignitions switch, then remove it.

Press LOCK then UNLOCK on the vehicle door lock control switch at 1 second intervals 5 times.

close and re-open drivers door.

Press LOCK and UNLOCK on the vehicle door lock control switch at 1 second intervals 5 times

Insert Key into ignition switch.

Switch ignition ON and OFF once to program a remote transmitter code while retaining the original codes or twice to program a remote transmitter code while erasing the original codes. three times to check how many remote transmitters are currently registered, or 5 times to erase all registered codes.

Remove Key from ignition switch.

System should now lock and unlock vehicle. Once, twice or five times depending which mode has been selected. It will lock and unlock one to four times slowly, to indicate the number of remote transmitters registered if you chose option 3.

Press and hold remote transmitter LOCK and UNLOCK buttons at the same time.

Press LOCK remote button for 1 second: System should now lock and unlock vehicle once to confirm, twice to indicate registration has failed.

NOTE: to exit programming mode, close drivers door or insert key in the ignition.

NOTE: a maximum of 4 remote transmitters can be programmed