Truck is starting up but wont stay running, replaced fuel filter, fuel pump is turning on, check fuses, relay all is fine what else could it be?

Did you check base fuel pressure with a gauge before and after replacing the pump ? Is the pump getting power from the relay ?
The fuel filter is under the car and should have been replaced with the pump.

There are still many possibilities. The internal combustion engine is a complex mechanism. The timing could be off. All spark plugs must be firing. They must fire at exactly top dead center. The timing chain/belt must be in good working order, not worn or stretched. The cam shaft must not be worn out so the valves open and close correctly. the valve lifters must be working properly. the cylinder heads must have the same correct compression. A different compression indicates bad valves or head gasket. Piston rings must not be worn out or they will not provide adequate compression. the oil pump must circulate the oil to lubricate everything, and provide fluid for hydraulic lifters. Oil and filters must be clean and the correct type for engine and climate.

sounds like a fuel problem. could be a fuel shut off switch, fuel pump relay, fuel pump. Possible bad electrical plug connection to pump

The problem with running out of gas is, the driver keeps trying to start the engine when the tank is empty and it burns up the fuel pump. Turn the key on and listen very closely for a hum or buzz coming from the back or underneath the car. This would indicate the pump is running, No sound may mean the pump is not running. Find the fuel pump relay on the fuse block under the hood and swap it with another relay to see if that has any effect. Also check the fuse panel for a blown fuse. If all else fails, get a can of starting fluid, remove the air filter, and spray the fluid into the intake duct while at the same time craning the starter, The engine should start. If it starts and dies, do this 3 or 4 times. If the engine still wont stay running, you may have to replace the fuel pump.

fuel may contain dust which block.

yes you should be able to hear the fuel pump run for about 5 seconds once the key is turned to the on pos. check to make sure you have spark. if you do try having someone spray air intake or carb cleaner into intake manifold while you crank. If the truck starts right up for a second (or stays running as you keep spraying) Id say you have a bad fuel pump and id change the sending unit also. (First check the fuel pump fuse and fuel pump relay) GMC and Chevy are nororiously known for having bad fuel pump/sending unit problems. I have prob changed over 60 myself.

sounds alot the the pcm it controls the fuel pump and ign system but the anti theft would keep it from starting because the key has a transponder in it programmed for that vehicle and that would kill all ign if triggered

MAKE YOU HEAR FUEL PUMP RUNNING WHEN TURN ON IGNITION KEY. IF NOT CHECK FUSE AND RELAY.IF YOU HEAR PUMP RUNNING. CHECK FUEL PRESSURE.IT SHOULD 36 TO 40 PSI.IF NOT REPLACE FUEL FILTER.IF FUEL PRESSURE IS STILL LOW FUEL PUMP IS BAD.

Check your battery connections, and your grounds for loose connections. This will cause the system to go haywire.

Fuel pump may be getting weak. If pressure is not high enough the injectors wont open.