Running great but shut down mid ride. Acted Like the kill switch was hit. Checked the switch it was fine. Started right back up. Ran for another minute then shut down again. Plugs have spark, fuel appears fine, thoughts?

Electrical doesn't affect the engine mechanically. Besides making it run rough or shutting it down. Engine mechanical does affect the electronics though. Sounds like you have an electrical problem that needs attention. Also sounds like you have an engine that just threw rod/main bearings. At 4500 miles, I hope you have a warranty on this engine.

Alternator is not charging battery starts a car and then alternator runs all power needs...

Change your fuel pump

check for vacuum leaks

I had the same problem but I did two fixes for it (1) when I bought the truck several years ago the duel tank switch was pushed in but i never fixed it and just would switch tanks with the switch pushed into the dash. after awhile it acted like it didn't know what tank to draw from point is i finally replaced the switch and it ran, but still ran rough, (2) on the left side of the motor their is an EGR valve (it was green colored vacum hose) I replaced that vacum hose and now it runs great.

I had the same problem with mine. I installed a fuel pressure gauge, and drove around until the problem started. The truck should be running between 48 to 56 lbs. of fuel pressure. Mine ran at idle at 42lbs. , not even high enough. Drove it for about 20 minutes, and it started to stumble. Fuel pressure dropped to 30lbs, 20 lbs - then all the way down to 2lbs. I shut it off, and it would not start back up. 30 seconds later, I turned the key and it came up to 10lbs. press. 10 more seconds 20lbs. After almost a minute, it came up to 42 lbs. started and I drove away. I replaced the fuel pump assemb. on 7/3/2008. Drove it around,and the problem is gone. Mine is a flex fuel, and the pump retails for $668.00. I did find a AC Delco pump for $221.00. I hope this helps.

Pull the starter and, have the starter solenoid checked

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i ended up taking the carberator off and found a piece of dirt in one of the jets, cleaned it out with break cleaner and put it back together and everything ran great.

we'll assume fuel is good..leaving spark and air..and management of systems(computer /sensors)...so the speedo cable was disconnected? try taking it loose again , test drive and report back please