We cannot get fuel to the engine

My guess is that after it ran out of gas, the key was in the forward position for a while and you unknowingly interrupted the antitheft system. Try to reset it.

RELEARN PROCEDURE:
Turn the key on, with the engine OFF.
Try to start the engine, then release the key to ON, Engine will not start.
Watch the security telltale, after about 10 mins, it will turn OFF.
Turn OFF the ignition, and wait 5 seconds.
Repeat steps 1 through 4 two more times for a total of 3 cycles/30 minutes. You must turn the ignition OFF for 30 seconds before attempting to start the vehicle after the 3 cycles. Then start the engine .


Do It Yourself GM Security bypass

Fuel filter in the right way? I would try cycling the key on and off several times leave on for 5 seconds, and off for 3-5 seconds. This will cycle the fuel pump and build up pressure, after 6-7 cycles try starting engine.

Your fuel pump is located inside the gas tank and every time you turn on the ignition switch the fuel pump will start and pressurize the fuel line for a regular starting cycle. But, since your fuel lines are totally empty. I would turn on the ignition for a 20 second period. then turn it off for a few minutes to let the system fuel system reset and then turn the key back on for the same amount of time and do this for at least 4 times. Each time you turn on the key if you have waited long enough to allow the fuel system to reset. This will in the end fill the fuel lines and fuel rail on the engine and then you should be able to crank the engine and start ok. do not crank the engine until after you have cycled the ignition key about four times and wait about 2 minutes in-between cycles.
Have a nice day, regards, Dennis

The Vehicle Control Module (VCM) electronically cuts off fuel to injectors when engine speed exceeds 5500 RPM . You should hear fuel relay click on firewall when key is turned on . Esay way to check fuel pressure without proper gauges is to diconnect fuel supply line at engine and cycle key , Have plenty of rags around fuel line .

Could be a weak fuel pump. Have you tried to start it using starting fluid ( spray this behind the MAF sensor to avoid damaging it...usually there is an air temp sensor that can be pulled out or a PCV valve hose connected that you can spray into ). Chances are you have good spark if it's trying to start but won't. Ultimately, a fuel pressure test would determine if you are getting adequate fuel pressure to start the engine. You could also try to cycle the ignition key from KEY OFF to KEY ON a few times to see if the fuel pump can build up enough pressure to improve the starting of the engine. Likely it won't actually start, but it might sound like it's closer to starting at first.

If you ran the tank dry then yes it is a fuel pump and you verified the problem with instant start fluid, you need a fuel pump

A couple of ideas-- you may have already considered. Is this an older car? If so, then some old cars get moisture in them on the electrical parts like say on the wiring harness or wiring. Another cause could be the battery is a bit weak. Go to Advance Auto or Autozone and get the battery tested. Then they getting the started tested. I hope this helps you! God bless!

My 2005 GMC does not have a fuel filter anywhere. Must be another great idea that an engineer came up with." we will tell them not having a filter cuts down on maintainence costs" As far as not having fuel to the engine, I would pull the line loose ane turn the key on to see if you have any fuel flow you might have to cycle the key several times as the pump will only run for 3 seconds with each key cycle, maybe a rubber line has collapsed on the inside, happens on brake lines all the time.

If engine is turning over when you cycle key to start, but engine won't start and run, then I wouldn't be looking at battery. Try cycling your key from off just to run position, where all dash lights etc come on, but not trying to start. Do that twice to on, then back to off, then turn key all the way to start, and see if it fires right up for you. If it does, change fuel filter if not done recently, and if that doesn't cure it, have fuel pressure tested, it may be low, indicating possible faulty/weak fuel pump. Let me know how it goes.

Does the engine crank but just not start? Or... are you cycling the ignition switch without trying to crank the engine? Based on the information you have given, I would first guess that the fuel pump may be going out. I say this because when you first turn the key on the pump primes the engine with pressurized fuel. If the pump is getting old, it may take a few power cycles to get it going. You can test this theory by having somebody listen near the rear of the car while you turn the key on for the first time. The fuel pump make a faint, yet distinctive high pitch noise that can be heard when you turn the key on. Try that first. Next thing you would try is checking the relays for proper function... starting with the fuel pump relay. Good luck.