1988 chevy S10 2.5L tbi

Checked timing? Ignition wires all good? Misfire under load may indicate bad wires.

you mean,cranks ok, but will not start and no fuel , right>?
s10 no fuel. 1988 ( S10 blazer )
please do say , what that means.
1: car cranks and will not start. so must be out of fuel?
(over 50 causes, or better is 10 or less tests (ask)
2: same, and fuel pressure is 0 psi (spec.9-13). gauged.?
3: fuel dribble test?
4: sparks good so tired test fuel and it ran on test fuel ok? proving
loss of fueling>?
5: injector dead cranking, (eyeballs)

which was it?

1988 cars in the USA are BIG TIME TRANSITION year.
we went from CARBS to EFI.
2.5L (what is E)?
gear cam, roller HLA lifters.
your car, USA , is TBI engine,
TBI started on THIS car in 1985 (1/2 and 1/2)
Throttle body injection
an on all TBI engines, one can see it inject with eyes.
does it?
if not it can be the following things.
1: no fuel pressure, 9-13pis.
2: ECU is cutting fuel. Pressure good cranking.
2a: ECU is sending error for bad crank/cam sensors, and cuts fuel.
2b: ECU sees rpm or tacho line dead.
2c. ECU sees TPS sensor output as 4v or more cranking, this cuts all fuel.
3: if ECU is happy, it sends 12vcd to the pump, cranking.
all tests must be dont cranking or chase tail.

Look for a cap on the fuel rail to purge air. Under cap will look like a tire valve, with fuel pump running depress center pin to bleed out air. If no fuel CK for plugged fuel filter.

Retime it. Put #1 cylinder at TDC of compression stroke. Pull number one spark plug: with finger over hole turn the crank with a socket and feel for the pressure buildup as engine turns. When you feel pressure, that means number one piston is rising on it's compression stroke. Now turn the crank on around until it is lining up the zero mark on the pointer scale. TDC of compression stroke.
Now put the distributor in so that the rotor when installed is pointing to the number one spark plug tower. Distributor shaft will turn slightly as it is installed, so start with shaft and rotor turned a bit back, so when slides into position, rotor is pointing directly to #1 plug tower. Keep playing with it until you get it right.
Good luck.

You first need to check the fuel pressure, an easy way to access this is to buy a can of spray starting fluid, spray it into the TBI throttle valve and if the truck starts and dies you have no fuel pressure. Replace the fuel; pump, and make sure you get the right pump, it is a low pressure system.

you can use wd40 and spray it into the intake and see if it fires, then you will need to find out if it a clogged line, fuel filter or fuel pump. Hope this helps Tim

Sounds like it. On new automobiles the fuel pump is in the gas tank, cools the pump, but you can disconnect the pump and put on an outside pump instead of pulling the gas tank and replacing gas pump and tank. Leave old pump in gas tank.

Distributor get taken out? Sounds like it's one tooth off at the gear between the camshaft and the distributor shaft.

sounds like ignition module inside of distributor cap under distributor rotor button.these do go bad and can easily be replaced.strong suspicion from your details that this is the culprit.

Check your EGR valve make sure that is working properly, if it is then go to the fuel pump, just a cheaper fix to go after the EGR then the fuel pump