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Check cam sensor, or inertia switch. It cuts off power to coil packs in the event of a crash. Also check fuel pump and fuel pump relay. Most Fords are wired to were if the fuel pump won't pump, it won't spark either. It's a safety measure that Ford builds in.
When you turn the key on you should beable to hear the fuel pump come on. Other than that you have a fuel pressure test port, looks just like a tire valve stem get a little probe press the valve after cranking fuel should come out strongly and not dribble out. If is doesnt seem to be firing your going to have check the coil pack for spark from the coil pack take one plug wire out and put it in a position that as you crank the vehicle you will be able to see spark jump or even hear give it a 1/4 air gap from its connection. If you dont have spark and your timing chain isnt broken you need to check for power the choice of tool is a test light.or volt meter. If you dont have either test tool we will go by sound when you turn the key on the engine fuse box has relays do you hear them click. That click noise will be fuel pump relay and PCM relay for power inpect those relays for corrode connections you mainly have a power problem and inspect for proper ground a missing ground can also cause the ECM to not fire the coils
If you confirmed spark is there, and you hear fuel pump working, I'd still try spraying WD-40 in throttle body intake for a couple of seconds, when it won't start, just to see if it kicks over, just in case pump is running but not up to pressure. If it fires for a second or 2 with WD-40, then you know lack of fuel is the problem.
The code description is a giveaway.
It could be one of the coils on the coil pack. Most coils nowadays do two cylinders each. This way car makers can get away with one coil for two cylinders.(lowers costs) One spark fires the air fuel mix in one of the cylinders and the other will fire the cylinder on the exhaust stroke. If the coils are removable, and you are fairly handy with cars,switch two around, the problem will follow the bad coil.