How do i replace the ignition in a 1995 jeep cherokee?
Not sure about the 1995, but the later system for sure needed the dealer's scan tool to re-program for a new key. The key reader, in the steering column needs to send the right signal to the computer or it will not start. If you really lost all the keys, better get two from the dealer and have them reprogram both at the same time. Around here its $200 to reprogram 2 keys (with remotes).
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