My 2000 GMC Sierra will not Crank

your testing is no good. (no engine told at all)
the ECM ,only injects using this logic.,

1: fuses good
2: ECM good (i bet yes)
3: CKP and CMP senors dead.
4: if the ECM sees spark dead it cuts all fuel to prevent as seen on TV "CRASH AND BURN" and by LAWs on this fact.
5: some cars have Injector buffer modules between ECM and injector rails.(LOOK OR READ THE FSM)
6: fuel pump dead.
7: fuel filters clogged or it and injectors too (they have 10micron screens)
8: have a NOID light? to see if injectors are not fired by ECM?
the injector plugs all have 12vdc on one pin, do they if not fuse blowN, #1 AGAIN.. USING A DMM, METER.

mostly this list works too BELOW.. (noid lamp fails)
fuses
ckp and or CMP sensor dead. The crank and cam must spin !!!!
if CMP is dead and cam does not spin, well that be cam drive dead.

spark dead, if spark is dead ECM detects it dead and fueling is banned,(blocked)by laws. (fire avoided , win)
way3:
if NOID passes on all injectors (as will spark tests)
fuel pressure gone. we measure it. (bad pump, clogs or bad fuel)

if spark is good test fuel test works.
ever do test fuel on any engine using can-o-fuel or instant start fuel in a spray can, seen engine run for 3 seconds and sounds good.?
RTM FIRST? there are sure more causes, list is common, only. and hard logic truths.

https://eautorepair.net/Marketing/Default.asp

Did you check primary voltage at the ignition coil, pink wire, goes hot with key on. Fuse protected circuit. Use a test light to check for voltage with key on. Do you have voltage to fuel injectors, key on. Fuel injector fuse/ coil, according to my info.

Check to see if you are getting spark from the coil to the distributor. I suppose the engine is a 5.7 liter?If not getting spark to the cap, then check for power and ground pulse at the coil.If there is spark at the cap, replace the ignition rotor. If there is no power or ground pulse at the coil,check to see if the ignition rotor is spinning when the starter is engaged. If the distributor is not spinning while cranking the engine there are several more things you'll need to check,i.e.,distributor gear and pin as well as oil pump if the pin or gear are damaged.

Sounds like a bad crank position sensor or a bad camshaft position sensor.... If the sensors can't tell the ecm where the position the crankshaft or camshaft is, the ecm won't know when to send a spark. So the ecm won't send any spark.

For the ECM 1 fuse to open you obviously have a short to ground , start with the injector disconnected and see if ECM 1 fuse still blows.If it does disconnect crank sensor, also inspect wires for the injectors or any rub through wires here is a diagram

Sounds to me its time to replace your ecm

could be in the crank position sensor

just a thought shack

check the ecm fuse and power wire from starter

You may check the starter motor. Sometimes they draw to much current from the battery and cause it to drain down to soon and not allow current to go anywhere else to start.

The crankshaft postion sensor is right above the starter on the engine block. Either it got broken during the starter replacement or the connector is unplugged, no crank sensor equals no spark.