Question about 2005 Chevrolet Silverado 2500HD 2WD

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My truck is giving a P0202 and P2149 codes its a 05 chevy silverado 6.6 duramax

The truck will lose power and start knocking very loudly...does not have enough power to pull itself!! I can shut truck off for a little while and restart and the knocking and power loss goes away for a short period of time then starts all over...any help would be great, thanks

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